| 别名 | STING, 7K7, Endoplasmic reticulum interferon stimulator, ERIS, MITA |
| 产品类型 | Monoclonal |
| 基因名称 | transmembrane protein 173 |
| 经测试应用 | WB, IHC |
| 宿主 | Rabbit |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human STING |
| 理论分子量 | 42 kDa |
| 实际分子量 | 35-40 kDa |
| Gene ID(NCBI) | 340061 |
| GeneBank Accession Number | BC047779 |
| UNIPROT | Q86WV6 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:1000-1:5000 |
| 背景信息 | This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |