| 别名 | ACSL4, FACL4, EC:6.2.1.15, Arachidonate--CoA ligase, ACSL 4 |
| 产品类型 | Monoclonal |
| 基因名称 | acyl-CoA synthetase long-chain family member 4 |
| 经测试应用 | WB, IHC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human ACSL4 |
| 理论分子量 | 79 kDa |
| 实际分子量 | 72 kDa |
| Gene ID(NCBI) | 2182 |
| GeneBank Accession Number | BC034959 |
| UNIPROT | O60488 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. |