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YTHDF2 Recombinant antibody

  • 货号:
    RM20140
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名NY REN 2, HGRG8, DF2, CLL-associated antigen KW-14, CLL associated antigen KW 14
产品类型Monoclonal
基因名称YTH domain family, member 2
经测试应用WB, IF/ICC
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human YTHDF2
理论分子量62 kDa
实际分子量65-70 kDa
Gene ID(NCBI)51441
GeneBank Accession NumberBC002559
UNIPROTQ9Y5A9
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:25000
背景信息This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.