MDM2/HDM2 Rabbit Polyclonal antibody
MDM2, E3 ubiquitin-protein ligase Mdm2, EC:2.3.2.27, hdm2, p53-binding protein Mdm2
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货号：
AP20256 -
规格：
- 20ul
- 50ul
- 100ul
- 150ul
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价格：
￥0.00
产品参数
| 产品类型 | Polyclonal |
| 基因名称 | Mdm2 p53 binding protein homolog (mouse) |
| 经测试应用 | WB, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human MDM2 |
| 理论分子量 | 55 kDa |
| 实际分子量 | 70-80 kDa, 55-60 kDa, 40-50 kDa |
| Gene ID(NCBI) | 4193 |
| GeneBank Accession Number | NM_001145337.2 |
| UNIPROT | Q00987 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | WB：1:250-1:1500 |
| 背景信息 | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. |
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