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NQO1 Polyclonal antibody

  • 货号:
    AP20243
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名Azoreductase, DHQU, DIA 4, DIA4, DT diaphorase
产品类型Polyclonal
基因名称NAD(P)H dehydrogenase, quinone 1
经测试应用WB, IHC, IF/ICC
宿主Rabbit
种属反应性Human
免疫原A synthesized peptide derived from human NQO1
理论分子量31 kDa
实际分子量31 kDa
Gene ID(NCBI)1728
GeneBank Accession NumberBC007659‍
UNIPROTP15559
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:4000
背景信息This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.