| 别名 | Azoreductase, DHQU, DIA 4, DIA4, DT diaphorase |
| 产品类型 | Polyclonal |
| 基因名称 | NAD(P)H dehydrogenase, quinone 1 |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human NQO1 |
| 理论分子量 | 31 kDa |
| 实际分子量 | 31 kDa |
| Gene ID(NCBI) | 1728 |
| GeneBank Accession Number | BC007659 |
| UNIPROT | P15559 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:4000 |
| 背景信息 | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |