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Cyclin D1 Polyclonal antibody

Cyclin D1 Polyclonal antibody

货号：
AP20238
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书

产品参数

别名	CCND1, B cell lymphoma 1 protein, B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene
产品类型	Polyclonal
基因名称	cyclin D1
经测试应用	WB, IHC, IF/ICC
宿主	Rabbit
种属反应性	Human, Mouse, Rat
免疫原	A synthesized peptide derived from human cyclin D1
理论分子量	34 kDa
实际分子量	34 kDa
Gene ID(NCBI)	595
GeneBank Accession Number	BC000076‍
UNIPROT	P24385
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:500-1:5000
背景信息	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers.

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