| 别名 | FBL, EC:2.1.1.-, FIB, FIB1, FLRN |
| 产品类型 | Polyclonal |
| 基因名称 | fibrillarin |
| 经测试应用 | WB, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human Fibrillarin |
| 理论分子量 | 34 kDa |
| 实际分子量 | 34 kDa |
| Gene ID(NCBI) | 2091 |
| GeneBank Accession Number | BC019260 |
| UNIPROT | P22087 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:3000 |
| 背景信息 | This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. |