>>

>>

>>

>>

JNK Polyclonal antibody

JNK Polyclonal antibody

货号：
AP20225
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书

产品参数

别名	c Jun N terminal kinase 1, JNK 46, JNK1, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, MAPK8, PRKM8, SAPK1
产品类型	Polyclonal
基因名称	mitogen-activated protein kinase 8
经测试应用	WB, IHC, IF/ICC
宿主	Rabbit
种属反应性	Human, Mouse
免疫原	A synthesized peptide derived from human JNK
理论分子量	48 kDa
实际分子量	40-55 kDa
Gene ID(NCBI)	5599
GeneBank Accession Number	‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍NM_138982‍
UNIPROT	P45983
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:250-1:1500
背景信息	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

推荐产品