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HMGB2 Polyclonal antibody

  • 货号:
    AP20223
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名HMG-2, HMG2, HMG 2, High mobility group protein B2, High mobility group protein 2
产品类型Polyclonal
基因名称high-mobility group box 2
经测试应用WB, IF/ICC
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human HMGB2
理论分子量24 kDa
实际分子量20-25 kDa
Gene ID(NCBI)3148
GeneBank Accession Number‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍BC001063‍
UNIPROTP26583
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:250-1:1500
背景信息This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.