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HLA-E Polyclonal antibody

  • 货号:
    AP20222
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名HLA 6.2, HLA E, HLA-6.2, HLAE, MHC class I antigen E
产品类型Polyclonal
基因名称major histocompatibility complex, class I, E
经测试应用WB, IHC, IF/ICC
宿主Rabbit
种属反应性Human, Mouse
免疫原A synthesized peptide derived from human HLA-E​
理论分子量40 kDa
实际分子量40 kDa
Gene ID(NCBI)3133
GeneBank Accession Number‍‍‍‍‍‍‍‍‍‍‍‍‍‍‍BC002578‍
UNIPROTP13747
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:1000-1:8000
背景信息HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.