| 别名 | HLA 6.2, HLA E, HLA-6.2, HLAE, MHC class I antigen E |
| 产品类型 | Polyclonal |
| 基因名称 | major histocompatibility complex, class I, E |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse |
| 免疫原 | A synthesized peptide derived from human HLA-E |
| 理论分子量 | 40 kDa |
| 实际分子量 | 40 kDa |
| Gene ID(NCBI) | 3133 |
| GeneBank Accession Number | BC002578 |
| UNIPROT | P13747 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:1000-1:8000 |
| 背景信息 | HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |