| 别名 | IKBA, IκB α, NFKBIA, I kappa B alpha, IkappaBalpha |
| 产品类型 | Polyclonal |
| 基因名称 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human IkB Alpha |
| 理论分子量 | 36 kDa |
| 实际分子量 | 36 kDa |
| Gene ID(NCBI) | 4792 |
| GeneBank Accession Number | BC002601 |
| UNIPROT | P25963 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |