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LIAS Polyclonal antibody

  • 货号:
    AP20138
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名HUSSY 01, LAS, LIAS, Lip syn, LIP1, Lipoate synthase, Lipoic acid synthase, lipoic acid synthetase, Lipoyl synthase, mitochondrial, LS
产品类型Polyclonal
基因名称lipoic acid synthetase
经测试应用WB, IHC
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human LIAS
理论分子量42 kDa
实际分子量34-42 kDa
Gene ID(NCBI)11019
GeneBank Accession NumberBC023635‍
UNIPROTO43766‍
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:2500
背景信息The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified.