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ZO-1 Polyclonal antibody

ZO-1 Polyclonal antibody

货号：
AP20106
规格：

20ul

50ul

100ul
价格：
￥0.00

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产品参数

别名	TJP1, ZO1, ZO 1, Tight junction protein ZO-1, Tight junction protein ZO 1
产品类型	Polyclonal
基因名称	tight junction protein 1 (zona occludens 1)
经测试应用	WB, IHC, IF/ICC
宿主	Rabbit
种属反应性	Human, Mouse, Rat
免疫原	A synthesized peptide derived from human ZO-1
理论分子量	195 kDa
实际分子量	230 kDa
Gene ID(NCBI)	7082
GeneBank Accession Number	BC111712
UNIPROT	Q07157
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:3000-1:30000
背景信息	This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms.

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