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PD-1/CD279 Monoclonal antibody

  • 货号:
    AM20246
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名CD279, PD1, PD-1, 4H4D1, hPD 1
产品类型Monoclonal
基因名称programmed cell death 1
经测试应用WB, IHC, IF-P
宿主Mouse
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human PD-1​
理论分子量32 kDa
实际分子量34 kDa
Gene ID(NCBI)5133
GeneBank Accession NumberBC074740‍
UNIPROTQ15116
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:25000
背景信息Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.