| 别名 | PCK1, PEPCK C, PEPCK1, PEPCKC |
| 产品类型 | Monoclonal |
| 基因名称 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human PCK1 |
| 理论分子量 | 69 kDa |
| 实际分子量 | 69 kDa |
| Gene ID(NCBI) | 5105 |
| GeneBank Accession Number | BC023978 |
| UNIPROT | P35558 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:2000 |
| 背景信息 | This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. |