| 别名 | PTK2, 2C5B9, EC:2.7.10.2, FADK 1, FAK1 |
| 产品类型 | Monoclonal |
| 基因名称 | PTK2 protein tyrosine kinase 2 |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human FAK |
| 理论分子量 | 119 kDa |
| 实际分子量 | 120-130 kDa |
| Gene ID(NCBI) | 5747 |
| GeneBank Accession Number | BC028733 |
| UNIPROT | Q05397 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. |