IL-2 Mouse Monoclonal antibody
IL2, 2F11C5, IL 2, interleukin 2, Interleukin-2
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货号：
AM20212 -
规格：
- 20ul
- 50ul
- 100ul
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价格：
￥0.00
产品参数
| 产品类型 | Monoclonal |
| 基因名称 | interleukin 2 |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human IL-2 |
| 理论分子量 | 18 kDa |
| 实际分子量 | 15 kDa |
| Gene ID(NCBI) | 3558 |
| GeneBank Accession Number | BC070338 |
| UNIPROT | P60568 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:2000 |
| 背景信息 | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |
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