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PKM2-specific Monoclonal antibody

  • 货号:
    AM20187
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名PKM2, PK-M2, PKM2 pyruvate kinase, muscle, PKM, Pyruvate kinase PKM
产品类型Monoclonal
基因名称PKM pyruvate kinase, muscle
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human PKM
理论分子量58 kDa
实际分子量58 kDa
Gene ID(NCBI)5315
GeneBank Accession Number‍‍‍‍‍‍‍‍‍NM_002654‍
UNIPROTP14618
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:15000
背景信息This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.