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TGFBR2 Monoclonal antibody

TGFBR2 Monoclonal antibody

货号：
AM20167
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书前往锐竞购买

产品参数

别名	2D5H7, EC:2.7.11.30, TbetaR-II, TGF beta receptor type 2, TGF-beta receptor type II
产品类型	Monoclonal
基因名称	transforming growth factor, beta receptor II
经测试应用	WB, IHC
宿主	Mouse
种属反应性	Human, Mouse, Rat
免疫原	A synthesized peptide derived from human TGFBR2
理论分子量	65 kDa
实际分子量	60-70 kDa
Gene ID(NCBI)	7048
GeneBank Accession Number	‍‍‍‍BC040499‍
UNIPROT	‍P37173‍
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:2500-1:10000
背景信息	The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

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