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IL-18 Monoclonal antibody

  • 货号:
    AM20158
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名IL18, Pre-IL18, 5C6F8, Iboctadekin, IFN-gamma-inducing factor
产品类型Monoclonal
基因名称IL-18
经测试应用WB, IHC, IF/ICC, IF-P
宿主Mouse
种属反应性Human
免疫原A synthesized peptide derived from human IL-18
理论分子量22 kDa
实际分子量10-15 kDa
Gene ID(NCBI)3606
GeneBank Accession Number‍BC007461‍
UNIPROT‍‍‍Q14116‍
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:5000
背景信息The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.