| 别名 | AMPK, AMPK alpha, AMPK Alpha 1, AMPK subunit alpha 1, AMPK1, AMPKa1, PRKAA1 |
| 产品类型 | Monoclonal |
| 基因名称 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| 经测试应用 | WB, IHC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human AMPK |
| 理论分子量 | 63 kDa |
| 实际分子量 | 60-70 kDa |
| Gene ID(NCBI) | 5562 |
| GeneBank Accession Number | BC012622 |
| UNIPROT | Q13131 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:1500 |
| 背景信息 | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |