| 产品类型 | Monoclonal |
| 基因名称 | sequestosome 1 |
| 经测试应用 | WB, IF, IHC |
| 宿主 | Mouse |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human alpha tubulin |
| 理论分子量 | 48 kDa |
| 实际分子量 | 55-60 kDa |
| Gene ID(NCBI) | 8878 |
| GeneBank Accession Number | BC017222 |
| UNIPROT | Q13501 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:4000-1:40000 |
| 背景信息 | This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. |
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