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BAX Monoclonal antibody

BAX Monoclonal antibody

货号：
AM20108
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书前往锐竞购买

产品参数

别名	Bcl-2-like protein 4, Bcl2-L-4, Apoptosis regulator BAX, 4G5E8
产品类型	Monoclonal
基因名称	BCL2-associated X protein
经测试应用	WB, IHC
宿主	Mouse
种属反应性	Human, Mouse, Rat
免疫原	A synthesized peptide derived from human BAX
理论分子量	21 kDa
实际分子量	15 kDa
Gene ID(NCBI)	581
GeneBank Accession Number	BC014175
UNIPROT	Q07812
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:5000-1:20000
背景信息	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

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