| 别名 | Cyclin, proliferating cell nuclear antigen |
| 产品类型 | 内参抗体 |
| 基因名称 | proliferating cell nuclear antigen |
| 经测试应用 | WB, IHC, IF-P |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human PCNA |
| 克隆类型 | Polyclonal |
| 理论分子量 | 31 kDa |
| 实际分子量 | 35 kDa |
| Gene ID(NCBI) | 5111 |
| GeneBank Accession Number | BC000491 |
| UNIPROT | P12004 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |