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COXIV Mouse Monoclonal antibody

  • 货号:
    AM20154
  • 规格:
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名COX4I1, 2A7B2, COX IV-1, COX4, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
产品类型内参抗体
基因名称cytochrome c oxidase subunit IV isoform 1
经测试应用WB, IHC
宿主Mouse
种属反应性Human
免疫原A synthesized peptide derived from human COXIV
克隆类型Monoclonal
理论分子量19 kDa
实际分子量10-15 kDa
Gene ID(NCBI)1327
GeneBank Accession NumberBC021236
UNIPROT‍‍P13073‍
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:1000-1:5000
背景信息Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.
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