| 别名 | COX4I1, 2A7B2, COX IV-1, COX4, Cytochrome c oxidase subunit 4 isoform 1, mitochondrial |
| 产品类型 | 内参抗体 |
| 基因名称 | cytochrome c oxidase subunit IV isoform 1 |
| 经测试应用 | WB, IHC |
| 宿主 | Mouse |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human COXIV |
| 克隆类型 | Monoclonal |
| 理论分子量 | 19 kDa |
| 实际分子量 | 10-15 kDa |
| Gene ID(NCBI) | 1327 |
| GeneBank Accession Number | BC021236 |
| UNIPROT | P13073 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:1000-1:5000 |
| 背景信息 | Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. |