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抑制剂/激活剂

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凋亡与自噬

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CP21R7 CP21

CP21R7是一种有效的、选择性的GSK-3β抑制剂，能有效激活经典Wnt信号通路。

货号：
TK0403
规格：

1mg

2mg

5mg

10mg

25mg
价格：
￥0.00

产品参数

CAS No.	125314-13-8
生物活性	CP21R7 is potent GSK-3β inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKCα, with an IC50 of 1900 nM.
分子式	C19H15N3O2
分子量	317.34
储存条件	Powder -20℃ 3 years
溶解性数据	DMSO : ≥ 32 mg/mL (100.84 mM)
体外研究	CP21R7 (Compound 9) is a selective inhibitor of GSK-3β, with an IC50 of 1.8 nM; the IC50 of CP21R7 against PKCα is 1900 nM. CP21R7 (CP21, 3 μM) potently activates canonical Wnt signaling with highest activity. CP21 significantly increases total levels of intracellular β-catenin. CP21 combined with BMP4 induces commitment of hPSCs towards mesoderm.
文献	暂无相关参考文献
纯度及产品资料	98%

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