>>

>>

抑制剂/激活剂

>>

凋亡与自噬

>>

Okanin 奥卡宁

Okanin 是 Coreopsis tinctoria 的有效成分。Okanin 通过抑制 TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。

货号：
TK0337
规格：

5mg
价格：
￥0.00

产品参数

CAS No.	484-76-4
生物活性	Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways
分子式	C15H12O6
分子量	288.25
运输条件	Room temperature in continental US; may vary elsewhere.
储存条件	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据	DMSO : 16.67 mg/mL (57.83 mM; Need ultrasonic)
体外研究	Okanin significantly inhibits LPS-induced TLR4 expression in BV-2 cells. Okanin inhibits the translocation of the NF-κB p65 subunit from the cytosol to the nucleus. Okanin significantly suppresses LPS-induced iNOS expression and also inhibites IL-6 and TNF-α production and mRNA expression in LPS-stimulated BV-2 cells.
文献	•Dis Markers. 11 Jan 2022.
纯度及产品资料	98%

推荐产品