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抑制剂/激活剂

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凋亡与自噬

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Ibotenic acid (RS-Ibotenic acid; DL-Ibotenic acid)

Ibotenic acid((RS)-Ibotenic acid; DL-Ibotenic acid) 是一种神经兴奋性氨基酸，最初是从鹅膏菌中分离出来的。它在 N-甲基-D-天冬氨酸 (NMDA) 和反式 ACPD) 或代谢型使君子氨酸 (Qm) 受体位点均表现出激动剂活性。

货号：
TK0225
规格：

1mg

5mg

10mg
价格：
￥0.00

产品参数

CAS No.	2552-55-8
生物活性	Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites.
分子式	C5H6N2O4
分子量	158.11
运输条件	Room temperature in continental US; may vary elsewhere.
储存条件	Powder -20°C 3 years
溶解性数据	H2O : 5 mg/mL (31.62 mM; Need ultrasonic) DMSO : 5 mg/mL (31.62 mM; Need ultrasonic)
体外研究	Ibotenic acid (Ibo) is capable of acting at both NMDA and trans-ACPD receptors in the CNS, although only activation of NMDA receptors is involved in Ibo neurotoxicity. Ibotenic acid is toxic to cortical neurons exposes for 5 min with an EC50=77.3±8 μM (n=5) as measured by release of lactate dehydrogenase to the culture media.
纯度及产品资料	98%

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