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抑制剂/激活剂

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凋亡与自噬

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Paclitaxel 紫杉醇

Paclitaxel 是一种天然抗肿瘤药，可稳定微管蛋白 (tubulin) 的聚合。Paclitaxel 可导致有丝分裂停滞和诱导细胞凋亡 (apoptosis)，最终导致细胞死亡。Paclitaxel 还可诱导细胞自噬 (autophagy)。

货号：
TK0104
规格：

1mg

5mg

10mg

50mg
价格：
￥0.00

产品参数

CAS No.	33069-62-4
生物活性	Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.
分子式	C47H51NO14
分子量	853.91
运输条件	Room temperature in continental US; may vary elsewhere.
储存条件	4°C, protect from light
溶解性数据	DMSO : 100 mg/mL (117.11 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble)
体内研究	Paclitaxel (1-20 mg/kg; i.p.; 1 time/2 days for five cycles) obviously induces liver metastases at the low-Paclitaxel group with little influence on primary tumor growth.
体外研究	Paclitaxel (20 nM; 48 hours) induces programmed cell death and exists a block at the G2/M phase of the cell cycle. Paclitaxel (20 nM; 48 hours) induces a consistent increase in the level of p53.
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纯度及产品资料	98%

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